A research team led by Prof. CHEN Yuxing and Prof. ZHOU Cong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) recently utilized single-particle cryogenic electron microscopy (cryo-EM) to decipher the 3D structure and molecular mechanism of the platelet drug transporter ABCC4. The study was published online in Nature Cardiovascular Research. In cases of vascular injury and bleeding, platelets need to be activated to promote blood clotting. Drugs such as aspirin and dipyridamole are commonly used in clinical practice to inhibit platelet function for the treatment of cardiovascular diseases. ABCC4 is an...